Increased density of human immunodeficiency virus type 1 coreceptors CCR5 and CXCR4 on the surfaces of CD4(+) T cells and monocytes of patients with Schistosoma mansoni infection.

نویسندگان

  • W Evan Secor
  • Amil Shah
  • Pauline M N Mwinzi
  • Bryson A Ndenga
  • Caroline O Watta
  • Diana M S Karanja
چکیده

Distribution of chemokine receptors CCR5 and CXCR4, which are also coreceptors for human immunodeficiency virus type 1 invasion of cells, was measured on the surfaces of CD4(+) T cells and monocytes in peripheral blood samples from a group of Kenyan car washers. Patients with active schistosomiasis displayed higher cell surface densities of these receptors than did cured schistosomiasis patients.

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عنوان ژورنال:
  • Infection and immunity

دوره 71 11  شماره 

صفحات  -

تاریخ انتشار 2003